Abstract--Skin diseases are among the most prevalent health concerns worldwide, yet conventional diagnostic methods are often costly, complex, and unavailable in low-resource settings. Automated classification using deep learning has emerged as a promising alternative, but existing studies are mostly limited to dermoscopic datasets and a narrow range of disease classes. In this work, we curate a large dataset of over 50 skin disease categories captured with mobile devices, making it more representative of real-world conditions. We evaluate multiple convo-lutional neural networks and Transformer-based architectures, demonstrating that Transformer models, particularly the Swin Transformer, achieve superior performance by effectively capturing global contextual features. T o enhance interpretability, we incorporate Gradient-weighted Class Activation Mapping (Grad-CAM), which highlights clinically relevant regions and provides transparency in model predictions. Our results underscore the potential of Transformer-based approaches for mobile-acquired skin lesion classification, paving the way toward accessible AIassisted dermatological screening and early diagnosis in resource-limited environments. Skin diseases are among the most common health problems worldwide, impacting millions of individuals across the world. According to the World Health Organization(WHO), more than 900 million people are affected by various skin conditions, with skin disorders ranking as the fourth leading cause of nonfatal disease burden worldwide [1]. These diseases range from mild infections to life-threatening chronic disorders.

Dairy owners spend significant effort to keep their animals healthy. There is good reason to hope that technologies such as computer vision and artificial intelligence (AI) could reduce these costs, yet obstacles arise when adapting advanced tools to farming environments. In this work, we adapt AI tools to dairy cow teat localization, teat shape, and teat skin condition classifications. We also curate a data collection and analysis methodology for a Machine Learning (ML) pipeline. The resulting teat shape prediction model achieves a mean Average Precision (mAP) of 0.783, and the teat skin condition model achieves a mean average precision of 0.828. Our work leverages existing ML vision models to facilitate the individualized identification of teat health and skin conditions, applying AI to the dairy management industry.

Deep learning models have achieved great success in automating skin lesion diagnosis. However, the ethnic disparity in these models' predictions needs to be addressed before deploying them. We introduce a novel approach, PatchAlign, to enhance skin condition image classification accuracy and fairness by aligning with clinical text representations of skin conditions. PatchAlign uses Graph Optimal Transport (GOT) Loss as a regularizer to perform cross-domain alignment. The representations obtained are robust and generalize well across skin tones, even with limited training samples. To reduce the effect of noise and artifacts in clinical dermatology images, we propose a learnable Masked Graph Optimal Transport for cross-domain alignment that further improves fairness metrics. We compare our model to the state-of-the-art FairDisCo on two skin lesion datasets with different skin types: Fitzpatrick17k and Diverse Dermatology Images (DDI). PatchAlign enhances the accuracy of skin condition image classification by 2.8% (in-domain) and 6.2% (out-domain) on Fitzpatrick17k, and 4.2% (in-domain) on DDI compared to FairDisCo. Additionally, it consistently improves the fairness of true positive rates across skin tones. The source code for the implementation is available at the following GitHub repository: https://github.com/aayushmanace/PatchAlign24, enabling easy reproduction and further experimentation.

Rapid development of disease detection models using computer vision is crucial in responding to medical emergencies, such as epidemics or bioterrorism events. Traditional data collection methods are often too slow in these scenarios, requiring innovative approaches for quick, reliable model generation from minimal data. Our study introduces a novel approach by constructing a comprehensive computer vision model to detect Mpox lesions using only synthetic data. Initially, these models generated a diverse set of synthetic images representing Mpox lesions on various body parts (face, back, chest, leg, neck, arm) across different skin tones as defined by the Fitzpatrick scale (fair, brown, dark skin). Subsequently, we trained and tested a vision model with this synthetic dataset to evaluate the diffusion models' efficacy in producing high-quality training data and its impact on the vision model's medical image recognition performance. The results were promising; the vision model achieved a 97% accuracy rate, with 96% precision and recall for Mpox cases, and similarly high metrics for normal and other skin disorder cases, demonstrating its ability to correctly identify true positives and minimize false positives. The model achieved an F1-Score of 96% for Mpox cases and 98% for normal and other skin disorders, reflecting a balanced precision-recall relationship, thus ensuring reliability and robustness in its predictions. Our proposed SynthVision methodology indicates the potential to develop accurate computer vision models with minimal data input for future medical emergencies.

This paper presents our team's participation in the MEDIQA-ClinicalNLP2024 shared task B. We present a novel approach to diagnosing clinical dermatology cases by integrating large multimodal models, specifically leveraging the capabilities of GPT-4V under a retriever and a re-ranker framework. Our investigation reveals that GPT-4V, when used as a retrieval agent, can accurately retrieve the correct skin condition 85% of the time using dermatological images and brief patient histories. Additionally, we empirically show that Naive Chain-of-Thought (CoT) works well for retrieval while Medical Guidelines Grounded CoT is required for accurate dermatological diagnosis. Further, we introduce a Multi-Agent Conversation (MAC) framework and show its superior performance and potential over the best CoT strategy. The experiments suggest that using naive CoT for retrieval and multi-agent conversation for critique-based diagnosis, GPT-4V can lead to an early and accurate diagnosis of dermatological conditions. The implications of this work extend to improving diagnostic workflows, supporting dermatological education, and enhancing patient care by providing a scalable, accessible, and accurate diagnostic tool.

With the continuous advancement of vision language models (VLMs) technology, remarkable research achievements have emerged in the dermatology field, the fourth most prevalent human disease category. However, despite these advancements, VLM still faces "hallucination" in dermatological diagnosis, and due to the inherent complexity of dermatological conditions, existing tools offer relatively limited support for user comprehension. We propose SkinGEN, a diagnosis-to-generation framework that leverages the stable diffusion (SD) method to generate reference demonstrations from diagnosis results provided by VLM, thereby enhancing the visual explainability for users. Through extensive experiments with Low-Rank Adaptation (LoRA), we identify optimal strategies for skin condition image generation. We conduct a user study with 32 participants evaluating both the system performance and explainability. Results demonstrate that SkinGEN significantly improves users' comprehension of VLM predictions and fosters increased trust in the diagnostic process. This work paves the way for more transparent and user-centric VLM applications in dermatology and beyond.

This paper outlines our submission to the MEDIQA2024 Multilingual and Multimodal Medical Answer Generation (M3G) shared task. We report results for two standalone solutions under the English category of the task, the first involving two consecutive API calls to the Claude 3 Opus API and the second involving training an image-disease label joint embedding in the style of CLIP for image classification. These two solutions scored 1st and 2nd place respectively on the competition leaderboard, substantially outperforming the next best solution. Additionally, we discuss insights gained from post-competition experiments. While the performance of these two solutions have significant room for improvement due to the difficulty of the shared task and the challenging nature of medical visual question answering in general, we identify the multi-stage LLM approach and the CLIP image classification approach as promising avenues for further investigation.

The rise of Artificial Intelligence creates great promise in the field of medical discovery, diagnostics and patient management. However, the vast complexity of all medical domains require a more complex approach that combines machine learning algorithms, classifiers, segmentation algorithms and, lately, large language models. In this paper, we describe, implement and assess an Artificial Intelligence-empowered system and methodology aimed at assisting the diagnosis process of skin lesions and other skin conditions within the field of dermatology that aims to holistically address the diagnostic process in this domain. The workflow integrates large language, transformer-based vision models and sophisticated machine learning tools. This holistic approach achieves a nuanced interpretation of dermatological conditions that simulates and facilitates a dermatologist's workflow. We assess our proposed methodology through a thorough cross-model validation technique embedded in an evaluation pipeline that utilizes publicly available medical case studies of skin conditions and relevant images. To quantitatively score the system performance, advanced machine learning and natural language processing tools are employed which focus on similarity comparison and natural language inference. Additionally, we incorporate a human expert evaluation process based on a structured checklist to further validate our results. We implemented the proposed methodology in a system which achieved approximate (weighted) scores of 0.87 for both contextual understanding and diagnostic accuracy, demonstrating the efficacy of our approach in enhancing dermatological analysis. The proposed methodology is expected to prove useful in the development of next-generation tele-dermatology applications, enhancing remote consultation capabilities and access to care, especially in underserved areas.

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented populations. Some have proposed that generative AI could reduce the need for real data, but its utility in model development remains unclear. Skin disease serves as a useful case study in synthetic image generation due to the diversity of disease appearance, particularly across the protected attribute of skin tone. Here we show that latent diffusion models can scalably generate images of skin disease and that augmenting model training with these data improves performance in data-limited settings. These performance gains saturate at synthetic-to-real image ratios above 10:1 and are substantially smaller than the gains obtained from adding real images. As part of our analysis, we generate and analyze a new dataset of 458,920 synthetic images produced using several generation strategies. Our results suggest that synthetic data could serve as a force-multiplier for model development, but the collection of diverse real-world data remains the most important step to improve medical AI algorithms.

Skin and subcutaneous diseases rank high among the leading contributors to the global burden of nonfatal diseases, impacting a considerable portion of the population. Nonetheless, the field of dermatology diagnosis faces three significant hurdles. Firstly, there is a shortage of dermatologists accessible to diagnose patients, particularly in rural regions. Secondly, accurately interpreting skin disease images poses a considerable challenge. Lastly, generating patient-friendly diagnostic reports is usually a time-consuming and labor-intensive task for dermatologists. To tackle these challenges, we present SkinGPT-4, which is the world's first interactive dermatology diagnostic system powered by an advanced visual large language model. SkinGPT-4 leverages a fine-tuned version of MiniGPT-4, trained on an extensive collection of skin disease images (comprising 52,929 publicly available and proprietary images) along with clinical concepts and doctors' notes. We designed a two-step training process to allow SkinGPT to express medical features in skin disease images with natural language and make accurate diagnoses of the types of skin diseases. With SkinGPT-4, users could upload their own skin photos for diagnosis, and the system could autonomously evaluate the images, identifies the characteristics and categories of the skin conditions, performs in-depth analysis, and provides interactive treatment recommendations. Meanwhile, SkinGPT-4's local deployment capability and commitment to user privacy also render it an appealing choice for patients in search of a dependable and precise diagnosis of their skin ailments. To demonstrate the robustness of SkinGPT-4, we conducted quantitative evaluations on 150 real-life cases, which were independently reviewed by certified dermatologists, and showed that SkinGPT-4 could provide accurate diagnoses of skin diseases.